Mutagens in the Witcher 3: Wild Hunt are quite different than previous Witcher games. There are now 4 Mutagen slots and a player can have up to 4 equipped at once. These can be changed and are not permanent. Each Mutagen comes in a color and if it is slotted next to Skills of the same color (adjacent slots) then it increases its effectiveness by 100% for each Skill slotted. Mutagen slots become unlocked as the player increases in level. Mutagens can also be used to brew powerful potions called Mutagen Decoctions.

Mutagens come in three tiers: lesser, normal, and greater. Three mutagens of one tier can be used to upgrade to the next tier. Ex: 3x Lesser Red Mutagen -> 1x Red Mutagen. There are also mutagens that drop straight from boss-type enemies, which can be found below. Note that these are similar to other mutagens when equipped, providing no extra bonus, but are unique in their ability to be crafted into decoctions. Also note that like other alchemical items, decoctions refill upon meditation with alcohol, and so must only be crafted once per playthrough.



Red Mutagens Add to Attack Power

Green Mutagens Add to Vitality

Blue Mutagens Add to Sign Intensity



Used For

Acquire/Where to find

Alghoul mutagen  Alghoul decoctions  Alghouls
 Ancient leshen mutagen  Ancient leshen decoctions Kernun
Woodland Spirit
other Ancient leshens
Basilisk mutagen Basilisk decoctions Basilisks
Blue mutagen Greater blue mutagens various monsters / Alchemy
Chort mutagen Chort decoctions Howler
other Chorts
 Cockatrice mutagen Cockatrice decoctions Shrieker
other Cockatrices
Doppler mutagen Doppler decoctions Imp
other Dopplers
Earth elemental mutagen Earth elemental decoctions Earth elementals
Ekhidna mutagen Ekhidna decoctions Melusine
other Ekhidnae
Ekimmara mutagen Ekimmara decoctions Sarasti
other Ekimmaras
Fiend mutagen Fiend decoctions Morvudd
other Fiends
Foglet mutagen Foglet decoctions Ignis Fatuus
other Foglets
Forktail mutagen Forktail decoctions The Dragon of Fyresdal
other Forktails
Grave hag mutagen Grave hag decoctions Mourntart
other Grave hags
Greater blue mutagen - Alchemy
Greater green mutagen - Alchemy
Greater red mutagen - Alchemy
Green mutagen Greater green mutagens various monsters / Alchemy
Griffin mutagen Griffin decoctions Royal griffin
Katakan mutagen Katakan decoctions Hubert Rejk
Leshen mutagen Leshen decoctions Kernun
other Leshens
Lesser blue mutagen Blue mutagens various monsters / Alchemy
Lesser green mutagen green mutagen various monsters / Alchemy
Lesser red mutagen red mutagen various monsters / Alchemy
Nekker warrior mutagen Nekker warrior decoctions Hagubman
Nightwraith mutagen Nightwraith decoctions Jenny o' the Woods
Cursed Mother
other Nightwraiths
Noonwraith mutagen Noonwraith decoctions Devil by the Well
The White Lady
other Noonwraiths
Protofleder mutagen - Protofleders
Red mutagen Greater red mutagens various monsters / Alchemy
Succubus mutagen Succubus decoctions Salma
other Succubi
Troll mutagen Troll decoctions Wham-a-Wham
other Trolls
Water hag mutagen Water hag decoctions Abaya
other Water hags
Werewolf mutagen Werewolf decoctions Morkvarg
other Werewolves
Wraith mutagen Wraith decoctions Wraiths
Wyvern mutagen Wyvern decoctions Wyverns


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    • Anonymous

      Do Sylvan's have a mutagen? I haven't seen or gotten one. They are Relicts like that fat sylvan posing as the peasants god in the ruins.

      • Anonymous

        Every drowner on Skellige will drop one random lesser mutagen. This way I got 50 lesser mutagens in 10 minutes. Did a short guide on that: If you lower lvl than go to the abandoned village south of Downwarren in Velen. There will be one alguhl, who drops all kinds of mutagens, also red ones. Meditate to fight him again.

        • Anonymous

          I have a lot of "named" mutagens llike "griphin mutagen", "nekker mutagen", ... I think I can remember, that I once saw a possibility to convert a "named" mutagen into a mutagen. As far as I remember it was in Alchemy and was "small mutagen" - converting a small named mutagen into an unnamed mutagen of the same color. But I patched the game and now I cannot find this anny more. I have lots and lots of named mutagens and cannot build normal muragens (for which I would need 3 small mutagens) or greater mutagens - even though I have enough e.a. green mutagens - but all of them not "named" small but Griphon, Nekker, ... But according to their Stats they are small mutagens. Anny clues what to do?

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