Alchemy Skills/Abilities are one of the 4 Skill Trees in the Witcher 3: Wild Hunt. These abilities improve Potions, Bombs, Mutagens and Oils. There are 5 Lines to this Skill Tree. Each Line has 4 skills and each skill has several ranks, leading to a wide variety of possible builds. You will have access to all Tier 1 Skills from the start of the game, but to be able to get put points into the Tier 2 Alchemy Skills you will need to spend 8 points in this branch. 20 points will unlock the Tier 3 skills and 28 points will unlock the final Tier.


Alchemy Skills




Enables the brewing and drinking of witcher potions.

heightened_tolerance.jpg Heightened Tolerance

Increases potion overdose threshold by 1%. Potion duration time: +5%

renewal.jpg Refreshment

Each Potion does imbibed heals 5% of maximum Vitality. Potion duration time: +5%

delayed_decay.jpg Delayed Recovery

Potion effects don't wear off until potion Toxicity falls to 90% of the maximum level. Potion duration time: +5%

Side Effects Side Effects

Imbibing a Potion gives 20% chance of activating the effects of another randomly-selected Potion, without additional toxicity cost. Potion duration time: +5%


Oil Preparation

Enables the creation of Oils that can be applied to swords.

Poisoned Blades Poisoned Blades

Oil applied to the blades gives a 3% chance of poisoning the target on each hit. The chance is greater the higher the level of Oil used. Potion duration time: +5%

placeholder.jpg Protective Coating

Adds +5% protection against attacks from the monster type the Oil targets. Potion duration time: +5%

Fixative Fixative

Blade Oils now have 33% more charges Potion duration time: +5%

Hunter Instinct Hunter Instinct

When Adrenaline Points are at their maximum, critical hit damage against the targeted enemy type is increased by 20%. Potion duration time: +5%


Bomb Creation

Enables the creation of handheld Bombs that can be thrown at enemies.

steady_aim.jpg Steady Aim

Time is slowed a further 15% while aiming Bombs. Potion duration +5%

Pyrotechnics Pyrotechnics

Bombs that do not usually inflict damage now deal 30 damage in addition to their normal effects. Potion duration time: +5%

Efficiency Efficiency

Increases maximum number of Bombs in each slot by 1. Potion duration time: +5%

Cluster Bombs Cluster Bombs

Upon detonation Bombs separate into explosive fragments. Number of fragments: 2. Potion duration time: +5%



Enables the extraction of Mutagens from the corpses of powerful Monsters. Witchers use these to grant their bodies new abilities.

placeholder.jpg Acquired Tolerance

Every known level 1 alchemical recipe, increases maximum Toxicity by 1. Potion duration time: +5%

placeholder.jpg Tissue Transmutation

When consumed, Mutagen Decoction increases maximum Vitality by 200 for Decoction's effective duration. Potion duration time: +5%

placeholder.jpg Synergy

Increases bonus for Mutagen in Mutagen slots by 10%. Potion duration time: +5%

Adaption Adaption

Extends effective duration of all mutagen Decoctions by 10%. Potion duration time: +5%


Trial of the Grasses

Mutation that lets witchers withstand the Toxicity of Potions that would kill normal people.

frenzy.jpg Frenzy

If Potion Toxicity is above 0, time automatically slows when an enemy is about to perform a counterattack. Potion duration time: +5%

Endure Pain Endure Pain

Increases maximum Vitality by 10% if toxicity exceeds the safe threshold. Potion duration time: +5%

Fast Metabolism Fast Metabolism

Toxicity drops 1 point(s) per second faster. Potion duration time: +5%

placeholder.jpg Killing Spree

If potion Toxicity is above 0, each opponent killed increases the chance for a critical hit by 10%. Potion duration time: +5%

    • Acquired Tolerance05 Jul 2016 09:37

      Acquired Tolerance is the best way to rise your maximum toxicity. You can level it up as you get to know more higher lvl recipes. I think this is the best ability of Alchemy skills.

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